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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7cc2189410f21fb5fbc31b4e6842b10bd13f000fe6aae533753a707e4121de' 
  AND token = 'R3l5p6TiQ2n+9F1eZqzMN/SNNGN9VfDhYD4TWHnr3hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}