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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d66591d0b53688158e991dd4f71112c40399b80a8fe3e982d6c27ef3f390dba' 
  AND token = 'DQmJCnqtln/EaTeaL6355D1pRkG2c1mPfkQCpA3rdoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}