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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09455585127a4f992d73b9a4766df88d9717571ead23f675dc2610e65a067afd' 
  AND token = 'fXbub4NMX4uW7GvL9jYN6/O4owTLZkdjO0VQl25FUac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}