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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00eb8cf4d79c79cfa4b360571e1e8900070ef6bb0fb17e178040e808e999f050' 
  AND token = 'V4heg5MnnbLeZ6UcFQD6YlXDzTQ+Om7MM8xhtilGXEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}