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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3a81199ff2892839b14fd00172811e4f27006f6e74ce2040ca7701cc445c35' 
  AND token = '9+9eek9WoFhe0OisEJfmW+5k2hPnF0sxQ+WpWWdCYIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}