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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f7a03422b1a163db84266f64ee77660263635a6ce71044b2c1b27f28fbe8bd' 
  AND token = 'uJg8xNF1Bb8Ir++c5fzZufrYhyIKIAuTYfhVdjGtlO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}