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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a34c3925e1726db6cad0b59ea1d3201ae2e05c78e68aa118f981359d992f0c25' 
  AND token = 'Bzbq6MZhmMM1CQWuOYD6Dw34FN+Gf1LkOt7xTxz9DSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}