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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e0eb395d2500dd2f62095e6c45740ea43247d003214b573c727ee04717b475' 
  AND token = 'gT6oPDdTAAGt+0bSSR55x/+VcGIHQMVEhllSahoayPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}