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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1237e294a9d5d3c557960e2f85922d4f8643312f04b22a13b704e25997c5c22' 
  AND token = 'gcHvhQ5e54rz5jf7p37Ct4YnGNR0Qe0Co18FvSfA8OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}