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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f141b6a8a02917c71560b00417a3a4d008e11a110f9be96fd34c116da73352b' 
  AND token = '+tKOA3O0GOkkR6vpdbZeBhFCukUqv1cu374UCdITkhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}