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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a20b6fc3a49bc3269e4b165b4adcd524f425de129d15a5cb0fb79632263be0' 
  AND token = 'MaQySX1EcISmCF6a+2YoQWJfpz2phqfFJeFvXALBfww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}