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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb48be7fe4d6b3f80239b2d9e97668be61a7d122449a888839fac6848a10094' 
  AND token = 'fwF906m8CMHkmGR9lW5TU4H7zwYy3t2XNI4h6jLZ9Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}