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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042974e4daa3d810e0cf10ceba0e679aaa45d6763901d8ab762e37bcae2f8f74' 
  AND token = 'Zq+BhfCc9oHRwj2VXcxLeumjoWRxDW6X5wELL0XhtaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}