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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c27159292e2c7d7909b8948c606cab5e750895d33ec20a8591f7ef27f84064' 
  AND token = 'vSIzjqRrkXc3j4IEySRdUUWsNeGa1aybaXNUJ+J+LkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}