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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595de3df65dec473d67cc6a1199fc0e157444542fca6e92ab4c72edbf1a1753b' 
  AND token = 'IbQB0TK2CCKebemxzLeHvaKosIXDwU3q0KpJH6hQhAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}