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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aaf33c060d85cefa35448b71a16ab3fd659f7a13a440cfce0120d20af24294' 
  AND token = 'CwvDwM9duKDwHIwz4YuIefPbMsOCRFrMo0y04fOVDPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}