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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4e25ece78aa9c41da6760e684e7b8bfa4dedf40cda3acabd097ff706b6e1a8' 
  AND token = 'BSrP3WEBcU66zW7mTcCpny0I2M/fBgRrCPjLXPUZnmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}