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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467a06ca76b1f8f0c293472fbbffe96b54e660a0664d1fab2adc01bb6a085e27' 
  AND token = '3VDtHpro5xFZtzJGnQ36mw5MBPtIy1nvCnL0svuzlNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}