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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8fc5765dca81a7578613fb9b9947cd8da5d8910ec06c1022a395ebad21016f' 
  AND token = 'ZXGiVDQbaGGYQ4UeUMDOL8bX39mmQLe/Gn8cDmZzu6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}