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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '317d7703ef62f1296d21af9863e0a0611eb2e143a7327b198a0bec3b25b5261f' 
  AND token = 'sQr2Nfo0WUZi5Vbh8/NTGEy8ViExzukMcaJJKZYMn0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}