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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '518172be88a3f444b47c290a1b3b8fd51f6de4f0ec860be2da09c3e354d1f01c' 
  AND token = '7ZR3zZiocr5Ocju+J0geagAUFRRW58soOdgNY8wd3ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}