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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '624ac86fe4980e27c32236bb6243ca36b2c9e3c8174f454a6507aab7cff3d882' 
  AND token = 'PHAYhV4EbQIim9+/tDTkviEoUgmh3712f5zK7ABI83Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}