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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af625c972fd695cc743ea66587ae90a7ce455ebc5486a4bc995f8a92c306183' 
  AND token = 'fsUdfiWR2XSiR52VtwkzAu24d0/+WNOBVZjI6PBedbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}