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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4457bff25de7f4f63325f34b598bf96e2887bd753e036313b3ba3889b5d76eba' 
  AND token = 'AA8pAJoVm3nHVqz2lgXoF85PcMWVLh0GSnkv2C9xydI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}