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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce926de87496b6b13f51d8177fd47383f7e31fd908f778cdf61a632488f4c9e6' 
  AND token = 'TP4SCSuDHNhKt+dJV27wTBMbydaJOiFg0k8D2xB1zb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}