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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7c2709f90fe981ee8ac5a13cf7fec1c843a7823cdb64e0d169390f25e1e7bd' 
  AND token = 'Qp5ZemM88GpeoFs5P5HDPMfgvOYHKlkSmB1fVNpYGck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}