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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9e50bc25fb4e5740b28c86c0d3c05ab7ac9d7da6baf6648e44de9056c3be41b' 
  AND token = 'Fg5JTN8J7t/cvfxlDMQjTIIDFti4hmmGKfE28WEITqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}