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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea533008598758e1ebac48af7d6b2b763bfc63c127353bb7021b2ee5d672ae2b' 
  AND token = 'KkNaDZCrATG/o6Yke7k7Xxz95ZGd4u4tqbv3DNnqRLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}