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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a02e21f31703ab131c13761a38ddb7d2532df57adf640e5f96323f9d05810e03' 
  AND token = 'QZ7JDpjjXkp/0hnCbNVUYK7UzT3kCEVGZNs+Wp+88RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}