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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b72734d9fe09e9f15d0befc361b8e840605d9c59a98b1655558e6bc7464ab4' 
  AND token = 'KvHlHW8abY8GIO3JgyNAzBvpti1PkEzj6ezGUsPxcqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}