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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a00944d43e8ac03cc92410153f20739c42e8894c240a38e4c71be2d06a2fefd' 
  AND token = '7IITUu+q1y30HU7rysAT6XLaXn1c7bgjg2MT27spxPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}