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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99ef8f58f6c04bacdf1858159149f5c3ba78a18f42d1b467c6e3c5deef6403e' 
  AND token = 'zSHwshPGeVPzKHAetDAXnoZmteZCbbU4vLpHvwEGxFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}