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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca785df7ad7b9197a40c7c715cd26b0e7d91c011ecf35e6ec396d869e7ce8e8' 
  AND token = 'uyr13WpRZ+rJzUmL29NMuZIZmNW6kFtWbI9pvL6Yrfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}