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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dda72165a1b5beceef8c5b4ce19ee866fed4b6f65ee3196a1dec0bd1b719fc3' 
  AND token = 'hBfU6eYzD/UuNg+ya/AX6WEw+R+xKYMDhdLrhMn4qlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}