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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '311cd0b9ecb860e9e5b18b729e083d5f009e18b9d3505dc45371630a199b2a35' 
  AND token = 'iORam+lVUvnpjwHtFSlnP7yhpNBtXKwMGx/Riwg1iL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}