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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108184083dcd9cb66a23a2afc1fd4cbee82d3b5cfc4e91bee0673ff29f579e07' 
  AND token = 'or9geJ1a9plzPQm24+MqdWdiLMtY9qZ4aTd8Z9SUrvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}