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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ba08be70a3a88a4bbf4976e6a52f269f1e0ae7769c970276dce5a19d0e98aeb' 
  AND token = 'VkfB9tcStf1X/v4VMvmG6yoL5lzVrmFpfdXR5/OhjxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}