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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821f34ad8426eda321a6483b291a3efa0c83f3d996eee89e775905310f348f32' 
  AND token = 'GG+yuvi1OFvBAoYwxUgmHRdAZEYNurE9m9gat7tShtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}