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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61a1372b18c9528889521f45e431ede637f3d3c34242c139f0bca24e48372de' 
  AND token = 'n4wg1UC2cUgnbDrwiidbN9QlhY+T5kbSLMHh/YUV9yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}