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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a66e4a25b9043bad534ddc65e28651556360af49a23e757180d75a798345a7' 
  AND token = 'kVaOm3pUkrq+PoRqn4eur1xJuPd45NOo3IQksi4jOg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}