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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4aec15e35fa6f962a0f86357013925d0352484a9762629611b0a903d35f8665' 
  AND token = 'asSKTmWjRDJm6J5zvyzIzU7HIEj0ZP+bF9h0iNfdxOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}