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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b03e9a56bb54dc31fcb3f1fab7388168ead74c7eb15ce396eb999e683981596' 
  AND token = 'MrChdTD96OtCkKvLULfc9mZOIiTV2O89BD3bGI+P7kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}