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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af99655b2a8aae912db36e84b4ce015f77c061cf9e6649ffc004116d0d9d3d8' 
  AND token = 'kpoQV773AYv1EIDaDZ72kxt9xGJeJLC2+6zcNQ3x0tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}