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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c660b384c96421f2c9263025c90f6b1451af3aef812149355be18f8025490ae' 
  AND token = 'ZT04sq4IB2Lxevz9GA3R6+qiUcNR+K7mDd4mVeLVliE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}