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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8573b1dcd40e8e00ca43527f94e0373db3b183b39cd109382a086d122ef3481a' 
  AND token = 'LnsWA1R6e82Pw1gbIIdDul/wrPkEDk+Ck1jwAhWmPqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}