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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866ab7a02625a4700a88cab4029a3a87f176b2c32dacff036cd746c04f947b21' 
  AND token = 'ZX0i8Jmzut5DDxsOWY0nB3AQL9dQY9uirMnveHtyay8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}