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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c720c15a9bed33688f7125e7f83694d9ae56aaadddc78a7ab9b7d160d8990ec4' 
  AND token = 'z83aCQxL4G1AtRNyHnXT0YVRcI/0/AXUUuCFmFJNPOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}