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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9820088e3b27acfeafc8d024da9c23221ad3e028800b9fdcd42e9da51791d770' 
  AND token = 'dipwk5B+rI1WPjV/pGNQMQPZFxmjplqX4txM/Utk09M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}