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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c695c68a67505ec8967bb3815828d5513ab98c4321c0ddcb4e1eddc463e6bf4' 
  AND token = 'qn6uIUTH8fq1ehHzYgBrg/Hb+f4MzOBODnHuB1OfnBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}