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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b72e2e56b54b85dcaf295bbad4e9d4ca8fca0fa449a556b9b0c313e015b6888' 
  AND token = 'P6BPqHZzHcbJ49QRte5CxHkFw+SbV8QZhU23zK37gdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}